5/14/2025
Last update
5/14/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
USERS' SCORE
Good
Based on 30 Reviews
8.1
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Magnesium(from 513 mg Buffered Magnesium Glycinate Chelate Complex [Magnesium Oxide and Magnesium Bisglycinate])
200 mg
48%
Magnesium-Rich Plants BlendOrganic Spinach LeafOrganic Chard LeafOrganic Okra FruitOrganic Quinoa Grain (Chenopodium quinoa)Organic Black Bean (Phaseolus vulgaris)Organic Pumpkin SeedOrganic Sunflower SeedOrganic Flaxseed
30 mg
**
Top Medical Research Studies
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
Most Useful Reviews
9
Pain relief success
115 people found this helpful
I never felt the effect of vitamins, but these exceeded my expectations. After experiencing leg muscle cramps, I was advised by the pharmacy to take Magne B6. Within a week, my pain decreased, and after 2-3 weeks, it completely vanished. I began to sleep better, my mood improved, and people around me noticed the changes. I have no discomfort while taking these vitamins, which is unusual for me as I dislike the aftertaste associated with most. I take two tablets in the morning and two in the evening.
Read More
9
Cramps relief
9 people found this helpful
I tried this form for the first time to relieve calf muscle cramps and anxiety. Both succeeded brilliantly; within a week, I had forgotten about cramps and my mood stabilised. It also helped a teenage athlete with muscle pain after training.
Read More
8.5
High-quality product
5 people found this helpful
I consider this product high quality due to its ingredients. It contains glycinate magnesium, crucial as many suffer from a deficiency. I deal with arthritis and constant muscle pain; this has positively impacted my sleep and relaxation. Each capsule is easy to take, and I plan to repurchase.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7
- All Researches
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Read More
7
We evaluated the effects of pamidronate therapy on children with osteogenesis imperfecta type III. Over the course of treatment, we saw reductions in bone pain, alongside a significant decrease in fracture incidence.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
The therapy positively impacted children's daily activities and their overall mobility. Importantly, the treatment was found to be safe, although some patients experienced mild side effects like low calcium levels and a fever. Overall, our findings suggest that bisphosphonate therapy is beneficial for management in these young patients.
Read More
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
Read More
User Reviews
USERS' SCORE
Good
Based on 30 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
9
Pain relief success
115 people found this helpful
I never felt the effect of vitamins, but these exceeded my expectations. After experiencing leg muscle cramps, I was advised by the pharmacy to take Magne B6. Within a week, my pain decreased, and after 2-3 weeks, it completely vanished. I began to sleep better, my mood improved, and people around me noticed the changes. I have no discomfort while taking these vitamins, which is unusual for me as I dislike the aftertaste associated with most. I take two tablets in the morning and two in the evening.
Read More
9
Cramps relief
9 people found this helpful
I tried this form for the first time to relieve calf muscle cramps and anxiety. Both succeeded brilliantly; within a week, I had forgotten about cramps and my mood stabilised. It also helped a teenage athlete with muscle pain after training.
Read More
8.5
High-quality product
5 people found this helpful
I consider this product high quality due to its ingredients. It contains glycinate magnesium, crucial as many suffer from a deficiency. I deal with arthritis and constant muscle pain; this has positively impacted my sleep and relaxation. Each capsule is easy to take, and I plan to repurchase.
Read More
9
Fatigue reduction noted
2 people found this helpful
This magnesium is my favourite! A magnesium deficiency leads to fatigue, irritability, and muscle spasms. I’ve noticed that the night cramps in my big toes, which troubled me two to three times monthly, have disappeared. It has helped alleviate irritability and sleep disturbances, and I take two capsules before bed.
Read More
9
Anxiety and spasm relief
2 people found this helpful
I love magnesium, particularly in glycine form, as it effectively calms nerves and aids sleep. This form works well for anxiety, muscle spasms, and leg pain without causing a laxative effect. The quality and price are excellent, and I highly recommend it for improving emotional wellbeing.
Read More
Frequently Asked Questions
9
Pain relief success
115 people found this helpful
I never felt the effect of vitamins, but these exceeded my expectations. After experiencing leg muscle cramps, I was advised by the pharmacy to take Magne B6. Within a week, my pain decreased, and after 2-3 weeks, it completely vanished. I began to sleep better, my mood improved, and people around me noticed the changes. I have no discomfort while taking these vitamins, which is unusual for me as I dislike the aftertaste associated with most. I take two tablets in the morning and two in the evening.
9
Cramps relief
9 people found this helpful
I tried this form for the first time to relieve calf muscle cramps and anxiety. Both succeeded brilliantly; within a week, I had forgotten about cramps and my mood stabilised. It also helped a teenage athlete with muscle pain after training.
7.5
Helps with fibromyalgia
8 people found this helpful
I have fibromyalgia syndrome and this magnesium somewhat relieved my bone pain. It's taken at night for sleep, as it causes drowsiness. I also take a different type of magnesium in the morning for activity. Thankful for the improvement in pain and mood.
9
Fatigue reduction noted
2 people found this helpful
This magnesium is my favourite! A magnesium deficiency leads to fatigue, irritability, and muscle spasms. I’ve noticed that the night cramps in my big toes, which troubled me two to three times monthly, have disappeared. It has helped alleviate irritability and sleep disturbances, and I take two capsules before bed.
0
Increased joint pain
I did not feel any improvement regarding sleep, muscle relaxation, or digestion. In fact, I experienced an increase in joint pain with regular use. I suspect the high magnesium levels resulted in elevated calcium levels too. I became diligent in taking potassium and increased my fruit intake, limiting daily use to a few times a week.
9
Anxiety and spasm relief
2 people found this helpful
I love magnesium, particularly in glycine form, as it effectively calms nerves and aids sleep. This form works well for anxiety, muscle spasms, and leg pain without causing a laxative effect. The quality and price are excellent, and I highly recommend it for improving emotional wellbeing.
9
Effective for bone pain
Good, excellent for bone pain, but I recommend doing so with medical advice to ensure safety.
7
We investigated how choline magnesium trisalicylate (CMT) helps alleviate bone pain in patients with metastatic cancer. In a carefully designed study involving 26 participants, we compared CMT against a placebo in a crossover format, measuring pain relief at multiple intervals after dosing.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
While we observed a significant reduction in pain just one hour post-treatment with CMT, other comparisons showed improvements that didn't reach statistical significance. This suggested that CMT might assist in managing bone pain, potentially complementing traditional opioids, but overall effectiveness is still under exploration.
7
Promising drug delivery for osteoporosis
We developed a novel drug delivery system combining denosumab and magnesium within metal-organic frameworks to target osteoarthritis. The framework showed good potential for loaded drug release, delivering about 72% of denosumab in just 8 hours.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
Additionally, it released magnesium ions, which are beneficial for bone formation. Our cytotoxicity tests demonstrated that the system is biocompatible and encourages cell growth over time. While our findings are promising for pain relief linked to osteoporosis, further studies are needed to confirm effectiveness in real-world scenarios.
References
- Alsaikhan F, Mahmoud MZ, Suliman M. Synthesis and characterization of novel denosumab/magnesium-based metal organic frameworks nanocomposite prepared by ultrasonic route as drug delivery system for the treatment of osteoporosis. Front Bioeng Biotechnol. 2023;11:1153969. 10.3389/fbioe.2023.1153969
- Jakubowska-Pietkiewicz E, Chlebna-Sokół D. New trends in the treatment of osteogenesis imperfecta type III - own experience. Ortop Traumatol Rehabil. 2008;10:593.
- Johnson JR, Miller AJ. The efficacy of choline magnesium trisalicylate (CMT) in the management of metastatic bone pain: a pilot study. Palliat Med. 1994;8:129.
